Prenatal screening tests are most suitable for couples who have information on their family history and the genetic mutations that might exist in the family which might eventually lead to Tay-Sachs. This form of screening is usually performed when both parents cannot be ruled out for being carriers of Tay-Sachs genes. Some cases of prenatal testing usually find either of the parents becoming aware of their status which enables the physician to rule out the possible carriers of the disease. The most commonly used methods in the prenatal screening of the disorder are the enzyme assay techniques which detect the level of activities in the HEX A (hexosaminidase) enzyme within the body as well as conducting a chorionic villus sampling (CVS) procedure (Walker, 2009)
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